Welcome to California Research Institute
At California Research Institute, we are dedicated to advancing medical knowledge and improving patient care through clinical research. Below, you'll find information about our currently enrolling studies. If you or someone you know is interested in participating, please contact us for more details.
We are currently enrolling for the following clinical research studies:
Non-Oncology
Study 1: Systemic Lupus Erythematosus (SLE)
This study evaluates the long-term safety and efficacy of XXXXXX in adult participants with active systemic lupus erythematosus.
Study 2: Moderate-to-Severe Systemic Lupus Erythematosus (SLE)
The purpose of this study is to evaluate the Efficacy, Safety, and Tolerability of XXXXXXXXX in Adult Subjects With Moderate-to-Severe Systemic Lupus Erythematosus (SLE).
Study 3: Systemic Lupus Erythematosus (SLE)
Study to Evaluate the Efficacy and Safety of XXXXXXXXXXX in Adult Participants With Active Systemic Lupus Erythematosus Receiving Background Nonbiologic Lupus Standard of Care.
Study 4: Pediatric Iron Deficiency Anemia
This study aims to evaluate the efficacy and safety of XXXXX XXXXXXXXXXX in children aged 0 to <18 years with iron deficiency anemia due to non-dialysis-dependent chronic kidney disease (NDD-CKD) or with iron deficiency anemia who are intolerant or unresponsive to oral XXXXXXX. The trial is designed as a prospective, open-label, multi-center study to provide comprehensive data on the effectiveness of XXXX XXXXXXXXXX in managing iron deficiency anemia in these populations.
Study 5: Bone Mineral Density (BMD)
This study aims to evaluate the efficacy and safety of the XXXXX or XXXXXXX (XXX) tablet (USA only) in female subjects aged 14 to 45 years who are postmenarcheal for at least two years and premenopausal. Participants who choose to take the trial medication will be compared to those who choose to use non-hormonal contraceptive methods. The study will enroll participants into two cohorts: adolescents aged 14-17 (Cohort 1) and adults aged 18-45 (Cohort 2). Please note: Cohort 2 is currently closed.
Oncology
Study 1: Breast Cancer
This study aims to compare the efficacy and safety of XXXXX-XXXX versus XXXXXX in treating estrogen receptor-positive, HER2-negative advanced breast cancer. This is for patients whose disease has progressed after prior endocrine-based treatment.
Study 2: Breast Cancer
This study is a Neoadjuvant Treatment for patients who are premenopausal with ER+/HER2- Breast Cancer.
Study 3: Solid Tumors
This study evaluates the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of XXXX-XXX alone and in combination with XXXXXXX in subjects with advanced MTAP-null solid tumors.
Study 3: Prostate Cancer
This study evaluates the efficacy and safety of XXXXX in combination with XXXXX compared to XXXXXXX-XXXX alone in treating subjects with metastatic castration-resistant prostate cancer (mCRPC).
Study 4: Non-Small Cell Lung Cancer
This study is for patients with advanced/metastatic non-small cell lung cancer (NSCLC) who have not received any treatment through the vein for the advanced disease.
Study 5: Colorectal Cancer
This study is for patients with Metastatic Colorectal Cancer with KRAS p.G12C Mutation.
Study 6: Myelofibrosis
Study Evaluating the Safety and Efficacy of XXXXXXXXXXX Plus XXXXXXXXXX vs XXXXXXX Plus XXXXXXXXXXX in JAK Inhibitor-Naïve Patients With Myelofibrosis.
Study 7: Head and Neck Squamous Cell Carcinoma
A study that consists of first-line therapy in patients with unresectable recurrent, or metastatic human papilloma virus 16, PD-L1 + Head and Neck Squamous Cell Carcinoma.
Study 8: Endometrial Cancer
A study to assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of XXXXXXX in patients with Advanced/Metastatic Solid Tumors.
Study 9: Cervical Cancer
A study to assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of XXXXXX in Subjects with Advanced/Metastatic Solid Tumors, specifically those with Cervical Cancer 1L.
Please note: These oncology studies do not represent all studies currently enrolling at our site. Contact us for a complete list of current studies.